FFL Helper / St Louis / Knoxville

STL → TYS

St Louis (STL) to Knoxville (TYS)

Compare one-way fares for flights from St Louis to Knoxville.

Lowest fare $261

Distance 391 mi

Flight time 37h 45m

Airports STL–TYS

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By month: October 2026 from $261

Price calendar

October 2026

From $261

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November 2026

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Upcoming dates

Knoxville TYS

$261

Oct 30, 7:59pm · 37h 45m · 2 stops

STL → TYS · Frontier Airlines

Tickets

About this route

This calendar shows dated one-way fares from St Louis to Knoxville. Use it to see which days are cheaper before you search tickets.

Flight time and airport codes on this page are for the sample itinerary we have on file. Always confirm the live routing when you book St Louis to Knoxville.